FACS XVIII

 

Monday:  June 13, 2022

7:00 – 8:00 a.m.	Buffet Breakfast
8:00 a.m.	Program Session 2:  Program Chair:  Thomas Bannister, Sripps Florida Enantioselective Reactions as an Approach to Increased Specificity
8:00 – 8:55	Plenary Lecture 1 and Discussion    Stellios Arseniyadis Direct and Highly Enantioselective Access to Gamma-Butenolides Through an Untapped C5-Selective Allylation of Siloxyfurans:  An Expedient Entry into O-Terpenoidal Natural Products
8:55 – 9:50	Plenary Lecture 2 and Discussion    Huw Davies Collaborative Studies in Catalyst-Controlled Site-Selective and Enantioselective C-H Functionalization
9:50 – 10:10 a.m.	Break
10:10 – 10:35	Keynote Lecture 5 and Discussion    Erica Benedetti Asymmetric Transfer Hydrogenation: a Highly Efficient Strategy to Access Planar Chiral
10:35 – 11:30	Plenary Lecture 3 and Discussion    Jean Suffert The Magic of the 4-Exo-Dig Carbopalladation:  How to Produce Complexity
11:30 – 11:55	Keynote Lecture 6 and Discussion    Nicholas Magnus Diastereoselective Pictet–Spengler Based Synthesis of a D1 Potentiator
12:00 p.m.	Adjourn (Lunch in the Emeline Dining Room)

1:10 p.m.	Program Session 3:  Program Chair:  Morgan Donnard, Assoc. Professor, Univ. of Strasbourg Creating Molecular Complexity for Increased Selectivity
1:10 – 2:05	Plenary Lecture 4 and Discussion    Marisa Kozlwoski Oxygen Driven Fragment Coupling for the Synthesis of Natural Products and Antibacterials
2:05 – 2:30	Keynote Lecture 7 and Discussion    Oliver Thiel Molecular Complexity as a Driver for Innovation in Pharmaceutical Process Development
2:30 – 2:55	Keynote Lecture 8 and Discussion    Adrien Quintard From Multi-Catalyzed Transformations to Smart Materials
3:00 p.m.	Adjourn
4:45 – 6:15 p.m.	Poster Session A
6:30 – 7:30 p.m.	Plated Dinner in the Emeline Dining Room

Tuesday:  June 14, 2022

7:00 – 8:00 a.m.	Buffet Breakfast
8:00 a.m.	Program Session 4:  Program Chair:  Nicholas Mgnus, Eli Lilly Natural Products as Leads for Oncology and Infectious Disease
8:00 – 8:55	Plenary Lecture 5 and Discussion    Louis Barriault Total Synthesis of Complex Polyoxygenated Diterpenes and Photoredox Transformations
8:55 – 9:50	Plenary Lecture 6 and Discussion    Dale Boger Vinblastine: Synthetic and Mechanistic Studies
9:50 – 10:10 a.m.	Break
10:10 – 11:05	Plenary Lecture 7 and Discussion    David Sarlah Methodology-Driven Synthesis of Anticancer Natural Products
11:05 – 12:00	Plenary Lecture 8 and Discussion    Erwan Poupon From Metabolomics to Bio-inspired Total Synthesis: Examples with Polycyclic Natural Products
	ANNOUNCEMENTS
12:00 p.m.	Adjourn for Lunch (Caravel Deli in Emeline Dining Room) Power Lunch Roundtable: Professor Marisa Kozlowski and Dr. Cathy Evans (Relay Therapeutics) will chair this discussion of issues confronting a new generation of women and underrepresented individuals. Special seating has been reserved for those who have expressed interest in attending.

1:10 p.m.	Program Session 5:   Program Chair:  Carina Sanchez, Senior Scientist, Novartis Institutes for Biomedical Research New Targets and Novel Approaches
1:10 – 2:05	Plenary Lecture 9 and Discussion    Maria Duca Targeting Non-Coding RNAs with Synthetic Small Molecules for Innovative Therapeutic Applications
2:05 – 3:00	Plenary Lecture 10 and Discussion    Boris Vauzeilles Detecting Pathogens and Reactive Oxygen Species Using Chemical Biology
3:00 – 3:25	Keynote Lecture 9 and Discussion    Fabien Rodier A Journey in Sanofi Route Scouting Programs – Technology and Science Driven Approach
3:25 p.m.	Adjourn
4:30 – 6:30 p.m.	FACS XVIII “Tastings Event”* and Poster Session B *A tasting of French wines and American craft cheeses.  Wines for this tasting event have been donated without consideration for any in-kind reciprocity.  Alcohol must be served exclusively by licensed Emeline personnel.
7:00 p.m.	Dinner (Conferees will be free to partake of the varied offerings within the Charleston Historic District.)

Wednesday, June 15, 2022

7:00 – 8:00 a.m.	Buffet Breakfast
8:00 a.m.	Program Session 6:  Program Chair:  Seva Rostovtsev, Director, FMC Corporation Advances in Heterocyclic Chemistry and Novel Pharmacophores
8:00 – 8:25	Keynote Lecture 10 and Discussion    Alex Radosevich Synthetic Methods Driven by the P(III)/P(V) Redox Couple
8:25 – 9:20	Plenary Lecture 11 and Discussion    Sami Lakhdar Mechanistically Driven Development of Carbon–Carbon & Carbon–Heteroatom Bond Forming Reactions
9:20 – 10:15	Plenary Lecture 12 and Discussion    John Vederas Synthesis of Cyclic Bioactive Peptides, Their Analogs and Unusual Amino Acid Building Blocks
10:15 – 10:30 a.m.	Break
10:30 – 11:25	Plenary Lecture 13 and Discussion    Marine Desage-El Murr Interfacing Redox Catalysis with the Metalloenzymatic Reactivity Toolbox
11:25 – 12:20	Plenary Lecture 13 and Discussion    Nicholas Meanwell Inhibitors of HIV-1 Maturation
12:00 p.m.	Adjourn for Lunch (Caravel Deli in Emeline Dining Room)

1:30 p.m.	Program Session 7:   Program Chair:  Xianglin Shi, Chief Technology Officer, Leal Therapeutics Molecules as Sensors and Probes
1:30 – 1:55	Keynote Lecture 11 and Discussion    Martin Schnermann Harnessing Cyanine Chemistry for Dynamic & Multicolor Imaging
1:55 – 2:50	Plenary Lecture 15 and Discussion    Mike VanNieuwenhze Visualization of Bacterial Cell Wall Synthesis and Cell Division with Fluorescent D-Amino Acids
2:50 – 3:15	Keynote Lecture 12 and Discussion    Kevin Meyer Creating a New Class of Fungicides
3:20 p.m.	Adjourn (Free time to explore Historic Charleston)
7:00 p.m.	Conference Banquet in Emeline Dining Room